These are my first to projects ever on Photoshop, so please critique and I will take it into account and try to fix it!
Thanks





Oh, by the way, BiO is another forum name I have.

first one is okay. but your smudging gives it absolutely no flow. it appears like you smudged (or brushed) a background and then placed a render on top. it just doesn't work for me.

second one is bad compared to the first one. The render quality is terrible, dont use a render like that. you made no attempt to blend the render either. The background has way different colors and is completely random compared to the render. and so it doesnt fit. You also need to fix the lighting up.

First suggestion: Border.
With a few exceptions, I'll just about always advocate, at the very least, a 1px black-line border. ;P Though in the case of this, something slightly more obnoxious would be in order, since black would meld with parts of the image.
First one seems kind of random. Find a smaller biohazzard symbol, I might suggest, or else have some effect going on where it cuts off, instead of just... not.
The background, as SiN mentioned, seems kind of random, and, visually, it clashes with the focus. It seems to hold no sense of pattern - and while you may be going for a relatively "chaotic" appearance, it bears noting that, something people recognize naturally, almost any random splatter will have some degree of order or tendencies in it.

...
Also, I'm dehydrated, low blood sugary, sleep deprived, and generally exhausted, so I'll probably be thinking, "WTF? I look like an idiot" when I read this post later. =D

Eh so this is like your first sig? tbh i think its too early to be taking criticism until you've gotten yourself familiar with the program. Someone might be like "OMFG Clipping mask on the render and then Filter>diffuse>234332235." and you'd be like "teh wuts?"

play with it some moar.
http://www.good-tutorials.com/

Firstly, about 99% of signature-making is just style. It should always be critiqued, as improving it is generally an extremely straight-forward process, until one has such an understanding of the subject that they don't need to have the philosophy of crticism explained to them.
Secondly, you learn how to use a program in large part by... using it! Crazy prospect, I know.

edit: Hell, take my suggestions for example. A border. Anyone can do that. A more ideally sized image. Again, simple. Add some warping or blurring effect near the bottom of the image. ... Redo the entire signature, and design it such that it forms a coherent image. While that's a rather more tricky task, it is, in this case, a matter of skill, not of understanding one's software.
I don't even touch Photoshop and that makes some sense to me. lolwut.