There is not a whole lot the United States or Russia could do to stop a nuclear warhead equipped to a missile heading from Israel to Pakistan.

Send in Sam Fisher with the algorithm to predict the best way to get rid the threat.

You want prediction of the future? Here's mine:
Isreal and Pakistan will not start a nuclear war in a reasonable amount of time, say 20 years.

Even those guys have something called inhibition level. If they would drop nukes on the other country they would contaminate the whole middle east with radiation and probably more.

So, in 20 years, when nothing happened, think about 'ol NudeRaider and smile.